Association of Periconception Paternal Body Mass Index With Persistent Changes in DNA Methylation of Offspring in Childhood
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation of vomiting in pregnancy with body mass index and quality of life
Introduction: It is believed that between 50% to 80% of pregnant women, suffer from nausea and vomiting during pregnancy. Nausea and vomiting of pregnancy decrease the ability of functioning, where the degree of this limitation is associated with severity of the symptoms. The aim is to assess the effect of body mass index (BMI) on the tendency of pregnant women to vomit and the effect of ...
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متن کاملPaternal Body Mass Index (BMI) Is Associated with Offspring Intrauterine Growth in a Gender Dependent Manner
BACKGROUND Environmental alternations leading to fetal programming of cardiovascular diseases in later life have been attributed to maternal factors. However, animal studies showed that paternal obesity may program cardio-metabolic diseases in the offspring. In the current study we tested the hypothesis that paternal BMI may be associated with fetal growth. METHODS AND RESULTS We analyzed the...
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ژورنال
عنوان ژورنال: JAMA Network Open
سال: 2019
ISSN: 2574-3805
DOI: 10.1001/jamanetworkopen.2019.16777